CFTR-mediated halide transport in phagosomes of human neutrophils

Chloride serves as a critical component of innate host defense against infection, providing the substrate for MPO-catalyzed production of HOCl in the phagosome of human neutrophils. Here, we used halide-specific fluorescent sensors covalently coupled to zymosan particles to investigate the kinetics...

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Detalhes bibliográficos
Main Authors: Painter, Richard G., Marrero, Luis, Lombard, Gisele A., Valentine, Vincent G., Nauseef, William M., Wang, Guoshun
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Host Defense & Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858676/
https://ncbi.nlm.nih.gov/pubmed/20089668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1009655
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