THE ROLE OF CHLORIDE ANION AND CFTR IN KILLING OF PSEUDOMONAS AERUGINOSA BY NORMAL AND CF NEUTROPHILS

Chloride anion is essential for myeloperoxidase to produce hypochlorous acid (HOCl) in neutrophils (PMNs). To define whether chloride availability to PMNs affects their HOCl production and microbicidal capacity, we examined how extracellular chloride concentration affects killing of Pseudomonas aeru...

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Detalhes bibliográficos
Main Authors: Painter, Richard G., Bonvillain, Ryan W., Valentine, Vincent G, Lombard, Gisele A., LaPlace, Stephanie G., Nauseef, William M., Wang, Guoshun
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901559/
https://ncbi.nlm.nih.gov/pubmed/18353929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0907658
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