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Neutrophil Extracellular Trap (NET)-Mediated Killing of Pseudomonas aeruginosa: Evidence of Acquired Resistance within the CF Airway, Independent of CFTR

The inability of neutrophils to eradicate Pseudomonas aeruginosa within the cystic fibrosis (CF) airway eventually results in chronic infection by the bacteria in nearly 80 percent of patients. Phagocytic killing of P. aeruginosa by CF neutrophils is impaired due to decreased cystic fibrosis transme...

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Detalhes bibliográficos
Main Authors: Young, Robert L., Malcolm, Kenneth C., Kret, Jennifer E., Caceres, Silvia M., Poch, Katie R., Nichols, David P., Taylor-Cousar, Jennifer L., Saavedra, Milene T., Randell, Scott H., Vasil, Michael L., Burns, Jane L., Moskowitz, Samuel M., Nick, Jerry A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164657/
https://ncbi.nlm.nih.gov/pubmed/21909403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023637
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