Cystic Fibrosis Transmembrane Conductance Regulator Recruitment to Phagosomes in Neutrophils

Optimal microbicidal activity of human polymorphonuclear leukocytes (PMN) relies on the generation of toxic agents such as hypochlorous acid (HOCl) in phagosomes. HOCl formation requires H(2)O(2) produced by the NADPH oxidase, myeloperoxidase derived from azurophilic granules, and chloride ion. Chlo...

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Main Authors: Zhou, Yun, Song, Kejing, Painter, Richard G., Aiken, Martha, Reiser, Jakob, Stanton, Bruce A., Nauseef, William M., Wang, Guoshun
Formáid: Artigo
Teanga:Inglês
Foilsithe: S. Karger AG 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717385/
https://ncbi.nlm.nih.gov/pubmed/23486169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346568
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