Cystic Fibrosis Transmembrane Conductance Regulator Recruitment to Phagosomes in Neutrophils

Optimal microbicidal activity of human polymorphonuclear leukocytes (PMN) relies on the generation of toxic agents such as hypochlorous acid (HOCl) in phagosomes. HOCl formation requires H(2)O(2) produced by the NADPH oxidase, myeloperoxidase derived from azurophilic granules, and chloride ion. Chlo...

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Bibliografski detalji
Glavni autori: Zhou, Yun, Song, Kejing, Painter, Richard G., Aiken, Martha, Reiser, Jakob, Stanton, Bruce A., Nauseef, William M., Wang, Guoshun
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717385/
https://ncbi.nlm.nih.gov/pubmed/23486169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346568
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