Cystic Fibrosis Transmembrane Conductance Regulator Recruitment to Phagosomes in Neutrophils

Optimal microbicidal activity of human polymorphonuclear leukocytes (PMN) relies on the generation of toxic agents such as hypochlorous acid (HOCl) in phagosomes. HOCl formation requires H(2)O(2) produced by the NADPH oxidase, myeloperoxidase derived from azurophilic granules, and chloride ion. Chlo...

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Detalhes bibliográficos
Main Authors: Zhou, Yun, Song, Kejing, Painter, Richard G., Aiken, Martha, Reiser, Jakob, Stanton, Bruce A., Nauseef, William M., Wang, Guoshun
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717385/
https://ncbi.nlm.nih.gov/pubmed/23486169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346568
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