Cystic Fibrosis Transmembrane Conductance Regulator Recruitment to Phagosomes in Neutrophils

Optimal microbicidal activity of human polymorphonuclear leukocytes (PMN) relies on the generation of toxic agents such as hypochlorous acid (HOCl) in phagosomes. HOCl formation requires H(2)O(2) produced by the NADPH oxidase, myeloperoxidase derived from azurophilic granules, and chloride ion. Chlo...

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Yun, Song, Kejing, Painter, Richard G., Aiken, Martha, Reiser, Jakob, Stanton, Bruce A., Nauseef, William M., Wang, Guoshun
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717385/
https://ncbi.nlm.nih.gov/pubmed/23486169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346568
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