Src Kinases Are Required for a Balanced Production of IL-12/IL-23 in Human Dendritic Cells Activated by Toll-Like Receptor Agonists

BACKGROUND: Pathogen recognition by dendritic cells (DC) is crucial for the initiation of both innate and adaptive immune responses. Activation of Toll-like Receptors (TLRs) by microbial molecular patterns leads to the maturation of DC, which present the antigen and activate T cells in secondary lym...

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Detalhes bibliográficos
Main Authors: Kuka, Mirela, Baronio, Roberta, Valentini, Sara, Monaci, Elisabetta, Muzzi, Alessandro, Aprea, Susanna, De Gregorio, Ennio, D'Oro, Ugo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901334/
https://ncbi.nlm.nih.gov/pubmed/20634889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011491
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