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Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

Innate immunity confers an immediate nonspecific mechanism of microbial recognition through germ line-encoded pattern recognition receptors (PRRs). Of these, Toll-like receptors (TLRs) and nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) have shaped our current understanding...

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Detalhes bibliográficos
Main Authors: Maisonneuve, Charles, Bertholet, Sylvie, Philpott, Dana J., De Gregorio, Ennio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151741/
https://ncbi.nlm.nih.gov/pubmed/25136133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400478111
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