Reactive Oxygen Species Promote Caspase-12 Expression and Tubular Apoptosis in Diabetic Nephropathy

Apoptosis of tubular epithelial cells contributes to the tubular atrophy that accompanies diabetic nephropathy. Reactive oxygen species (ROS) promote tubular apoptosis, but the mechanisms by which this occurs are incompletely understood. Here, we sought proapoptotic genes that ROS differentially upr...

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Bibliographische Detailangaben
Hauptverfasser: Brezniceanu, Marie-Luise, Lau, Cara J., Godin, Nicolas, Chénier, Isabelle, Duclos, Alain, Éthier, Jean, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao-Ling, Chan, John S.D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2010
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900966/
https://ncbi.nlm.nih.gov/pubmed/20299359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009030242
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