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Assessment of immunogenicity of romiplostim in clinical studies with ITP subjects
Romiplostim is an Fc-peptide fusion protein that activates intracellular transcriptional pathways via the thrombopoietin (TPO) receptor leading to increased platelet production. Romiplostim has been engineered to have no amino acid sequence homology to endogenous TPO. Recombinant protein therapeutic...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer-Verlag
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900600/ https://ncbi.nlm.nih.gov/pubmed/20155267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-010-0908-2 |
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