Assessment of immunogenicity of romiplostim in clinical studies with ITP subjects

Romiplostim is an Fc-peptide fusion protein that activates intracellular transcriptional pathways via the thrombopoietin (TPO) receptor leading to increased platelet production. Romiplostim has been engineered to have no amino acid sequence homology to endogenous TPO. Recombinant protein therapeutic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jawa, Vibha, Hokom, Martha, Hu, Zheng, El-Abaadi, Naglaa, Zhuang, Yao, Berger, Dietmar, Gupta, Shalini, Swanson, Steven J., Chirmule, Narendra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer-Verlag 2010
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900600/
https://ncbi.nlm.nih.gov/pubmed/20155267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-010-0908-2
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