Assessment of immunogenicity of romiplostim in clinical studies with ITP subjects

Romiplostim is an Fc-peptide fusion protein that activates intracellular transcriptional pathways via the thrombopoietin (TPO) receptor leading to increased platelet production. Romiplostim has been engineered to have no amino acid sequence homology to endogenous TPO. Recombinant protein therapeutic...

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Hlavní autoři: Jawa, Vibha, Hokom, Martha, Hu, Zheng, El-Abaadi, Naglaa, Zhuang, Yao, Berger, Dietmar, Gupta, Shalini, Swanson, Steven J., Chirmule, Narendra
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900600/
https://ncbi.nlm.nih.gov/pubmed/20155267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-010-0908-2
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