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Extensive DNA End Processing by Exo1 and Sgs1 Inhibits Break-Induced Replication
Homology-dependent repair of DNA double-strand breaks (DSBs) by gene conversion involves short tracts of DNA synthesis and limited loss of heterozygosity (LOH). For DSBs that present only one end, repair occurs by invasion into a homologous sequence followed by replication to the end of the chromoso...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900301/ https://ncbi.nlm.nih.gov/pubmed/20628570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001007 |
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