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Extensive DNA End Processing by Exo1 and Sgs1 Inhibits Break-Induced Replication

Homology-dependent repair of DNA double-strand breaks (DSBs) by gene conversion involves short tracts of DNA synthesis and limited loss of heterozygosity (LOH). For DSBs that present only one end, repair occurs by invasion into a homologous sequence followed by replication to the end of the chromoso...

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Autori principali: Marrero, Vanessa A., Symington, Lorraine S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900301/
https://ncbi.nlm.nih.gov/pubmed/20628570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001007
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