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An energetic tale of AMPK-independent effects of metformin

Metformin has become a mainstay in the modest therapeutic armamentarium for the treatment of the insulin resistance of type 2 diabetes mellitus. Although metformin functions primarily by reducing hepatic glucose output, the molecular mechanism mediating this effect had remained elusive until recentl...

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Detalhes bibliográficos
Main Authors: Miller, Russell A., Birnbaum, Morris J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898617/
https://ncbi.nlm.nih.gov/pubmed/20577046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43661
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