Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

The adipocyte-derived hormone adiponectin signals from the fat storage depot to regulate metabolism in peripheral tissues. Inversely correlated with body fat levels, adiponectin reduction in obese individuals may play a causal role in the symptoms of metabolic syndrome. Adiponectin lowers serum gluc...

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Hlavní autoři: Miller, Russell A., Chu, Qingwei, Le Lay, John, Scherer, Philipp E., Ahima, Rexford S., Kaestner, Klaus H., Foretz, Marc, Viollet, Benoit, Birnbaum, Morris J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104763/
https://ncbi.nlm.nih.gov/pubmed/21606593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45942
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