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Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P

Fragile X syndrome (FXS), resulting solely from the loss of function of the human fragile X mental retardation 1 (hFMR1) gene, is the most common heritable cause of mental retardation and autism disorders, with syndromic defects also in non-neuronal tissues. In addition, the human genome encodes two...

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Autores principales: Coffee, R. Lane, Tessier, Charles R., Woodruff, Elvin A., Broadie, Kendal
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Limited 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898537/
https://ncbi.nlm.nih.gov/pubmed/20442204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.004598
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