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In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation

Fragile X syndrome (FXS), caused by loss of the Fragile X Mental Retardation 1 (FMR1) gene product (FMRP), is the most common heritable cause of intellectual disability and autism spectrum disorders. It has been long hypothesized that the phosphorylation of serine 500 (S500) in human FMRP controls i...

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Detalhes bibliográficos
Main Authors: Coffee, R. Lane, Williamson, Ashley J., Adkins, Christopher M., Gray, Marisa C., Page, Terry L., Broadie, Kendal
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263990/
https://ncbi.nlm.nih.gov/pubmed/22080836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr527
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