Laddar...
Rhes, a Physiologic Regulator of Sumoylation, Enhances Cross-sumoylation between the Basic Sumoylation Enzymes E1 and Ubc9
We recently reported that the small G-protein Rhes has the properties of a SUMO-E3 ligase and mediates mutant huntingtin (mHtt) cytotoxicity. We now demonstrate that Rhes is a physiologic regulator of sumoylation, which is markedly reduced in the corpus striatum of Rhes-deleted mice. Sumoylation inv...
Sparad:
| Huvudupphovsmän: | , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2010
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898300/ https://ncbi.nlm.nih.gov/pubmed/20424159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.127191 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|