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Is Transthyretin a Regulator of Ubc9 SUMOylation?

Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investigated the Small Ubiquitin-like Modifier (SUMO)ylatio...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wieczorek, Elżbieta, Kędracka–Krok, Sylwia, Sołtys, Katarzyna, Jankowska, Urszula, Hołubowicz, Rafał, Seliga, Justyna, Ożyhar, Andrzej
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976990/
https://ncbi.nlm.nih.gov/pubmed/27501389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160536
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