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Is Transthyretin a Regulator of Ubc9 SUMOylation?

Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investigated the Small Ubiquitin-like Modifier (SUMO)ylatio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wieczorek, Elżbieta, Kędracka–Krok, Sylwia, Sołtys, Katarzyna, Jankowska, Urszula, Hołubowicz, Rafał, Seliga, Justyna, Ożyhar, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976990/
https://ncbi.nlm.nih.gov/pubmed/27501389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160536
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