DNA Repair and Global Sumoylation Are Regulated by Distinct Ubc9 Noncovalent Complexes

Global sumoylation, SUMO chain formation, and genome stabilization are all outputs generated by a limited repertoire of enzymes. Mechanisms driving selectivity for each of these processes are largely uncharacterized. Here, through crystallographic analyses we show that the SUMO E2 Ubc9 forms a nonco...

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Autors principals: Prudden, John, Perry, J. Jefferson P., Nie, Minghua, Vashisht, Ajay A., Arvai, Andrew S., Hitomi, Chiharu, Guenther, Grant, Wohlschlegel, James A., Tainer, John A., Boddy, Michael N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133251/
https://ncbi.nlm.nih.gov/pubmed/21444718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05188-11
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