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Semliki Forest Virus-Induced Endoplasmic Reticulum Stress Accelerates Apoptotic Death of Mammalian Cells

The alphavirus Semliki Forest virus (SFV) and its derived vectors induce apoptosis in mammalian cells. Here, we show that apoptosis is associated with the loss of mitochondrial membrane potential followed by the activation of caspase-3, caspase-8, and caspase-9. Cell death can be partially suppresse...

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書誌詳細
主要な著者: Barry, Gerald, Fragkoudis, Rennos, Ferguson, Mhairi C., Lulla, Aleksei, Merits, Andres, Kohl, Alain, Fazakerley, John K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898233/
https://ncbi.nlm.nih.gov/pubmed/20427528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02310-09
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