Semliki Forest Virus-Induced Endoplasmic Reticulum Stress Accelerates Apoptotic Death of Mammalian Cells

The alphavirus Semliki Forest virus (SFV) and its derived vectors induce apoptosis in mammalian cells. Here, we show that apoptosis is associated with the loss of mitochondrial membrane potential followed by the activation of caspase-3, caspase-8, and caspase-9. Cell death can be partially suppresse...

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Autori principali: Barry, Gerald, Fragkoudis, Rennos, Ferguson, Mhairi C., Lulla, Aleksei, Merits, Andres, Kohl, Alain, Fazakerley, John K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898233/
https://ncbi.nlm.nih.gov/pubmed/20427528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02310-09
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