Semliki Forest Virus-Induced Endoplasmic Reticulum Stress Accelerates Apoptotic Death of Mammalian Cells

The alphavirus Semliki Forest virus (SFV) and its derived vectors induce apoptosis in mammalian cells. Here, we show that apoptosis is associated with the loss of mitochondrial membrane potential followed by the activation of caspase-3, caspase-8, and caspase-9. Cell death can be partially suppresse...

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Hlavní autoři: Barry, Gerald, Fragkoudis, Rennos, Ferguson, Mhairi C., Lulla, Aleksei, Merits, Andres, Kohl, Alain, Fazakerley, John K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898233/
https://ncbi.nlm.nih.gov/pubmed/20427528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02310-09
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