PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response

The double-stranded RNA-activated protein kinase (PKR) is a key regulator of protein translation, interferon (IFN) expression and cell survival. Upon infection of vertebrate cells in continuous culture, the alphavirus Semliki Forest virus (SFV) initiates apoptosis and IFN synthesis. To determine the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Barry, Gerald, Breakwell, Lucy, Fragkoudis, Rennos, Attarzadeh-Yazdi, Ghassem, Rodriguez-Andres, Julio, Kohl, Alain, Fazakerley, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2009
Assuntos:
Animal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885058/
https://ncbi.nlm.nih.gov/pubmed/19264662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.007336-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados