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Differences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest Virus

The A7(74) strain of Semliki Forest virus (SFV; genus Alphavirus) is avirulent in adult mice, while the L10 strain is virulent in mice of all ages. It has been previously demonstrated that this phenotypic difference is associated with nonstructural protein 3 (nsP3). Consensus clones of L10 (designat...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Saul, Sirle, Ferguson, Mhairi, Cordonin, Colette, Fragkoudis, Rennos, Ool, Margit, Tamberg, Nele, Sherwood, Karen, Fazakerley, John K., Merits, Andres
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621116/
https://ncbi.nlm.nih.gov/pubmed/26311875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01186-15
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