Inhibition of Dengue Virus RNA Synthesis by an Adenosine Nucleoside

We recently reported that (2R,3R,4R,5R)-2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-hydroxy-methyl-tetrahydro-furan-3,4-diol is a potent inhibitor of dengue virus (DENV), with 50% effective concentration (EC(50)) and cytotoxic concentration (CC(50)) values of 0.7 μM and >100 μM, respecti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chen, Yen-Liang, Yin, Zheng, Duraiswamy, Jeyaraj, Schul, Wouter, Lim, Chin Chin, Liu, Boping, Xu, Hao Ying, Qing, Min, Yip, Andy, Wang, Gang, Chan, Wai Ling, Tan, Hui Pen, Lo, Melissa, Liung, Sarah, Kondreddi, Ravinder Reddy, Rao, Ranga, Gu, Helen, He, Handan, Keller, Thomas H., Shi, Pei-Yong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2010
विषय:
Antiviral Agents
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897296/
https://ncbi.nlm.nih.gov/pubmed/20457821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00140-10
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन