Stainless Steel Ions Stimulate Increased Thrombospondin-1-Dependent TGF-Beta Activation by Vascular Smooth Muscle Cells: Implications for In-Stent Restenosis

BACKGROUND/AIMS: Despite advances in stent design, in-stent restenosis (ISR) remains a significant clinical problem. All implant metals exhibit corrosion, which results in release of metal ions. Stainless steel (SS), a metal alloy widely used in stents, releases ions to the vessel wall and induces r...

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Detalles Bibliográficos
Main Authors: Pallero, Manuel A., Talbert Roden, Melissa, Chen, Yiu-Fai, Anderson, Peter G., Lemons, Jack, Brott, Brigitta C., Murphy-Ullrich, Joanne E.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2010
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895758/
https://ncbi.nlm.nih.gov/pubmed/20016205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000265565
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