An Oligomeric Equilibrium Intermediate as the Precursory Nucleus of Globular and Fibrillar Supramacromolecular Assemblies in a PDZ Domain

The equilibrium unfolding at neutral pH of the third PDZ domain of PSD95, as followed by DSC, is characterized by the presence of an equilibrium intermediate with clear signs of oligomerization. DLS and SEC measurements indicate that at 60–70°C small oligomers populate, showing a typical β-sheet far...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Murciano-Calles, Javier, Cobos, Eva S., Mateo, Pedro L., Camara-Artigas, Ana, Martinez, Jose C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
Protein
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895384/
https://ncbi.nlm.nih.gov/pubmed/20655855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.003
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky