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Equilibrium Unfolding of the PDZ Domain of β2-Syntrophin
β2-syntrophin, a dystrophin-associated protein, plays a pivotal role in insulin secretion by pancreatic β-cells. It contains a PDZ domain (β2S-PDZ) that, in complex with protein-tyrosine phosphatase ICA512, anchors the dense insulin granules to actin filaments. The phosphorylation state of β2-syntro...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379018/ https://ncbi.nlm.nih.gov/pubmed/22735534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.021 |
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