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Mechanisms of Pathogenesis in Drug Hepatotoxicity Putting the Stress on Mitochondria
Mitochondria play key roles in aerobic life and in cell death. Thus, interference of normal mitochondrial function impairs cellular energy and lipid metabolism and leads to the unleashing of mediators of cell death. The role of mitochondria in cell death due to drug hepatotoxicity has been receiving...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895369/ https://ncbi.nlm.nih.gov/pubmed/20368370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.10.2.7 |
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