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Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria
Drugs that cause liver injury often “stress” mitochondria and activate signal transduction pathways important in determining cell survival or death. In most cases, hepatocytes adapt to the drug-induced stress by activating adaptive signaling pathways, such as mitochondrial adaptive responses and ery...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622802/ https://ncbi.nlm.nih.gov/pubmed/23453390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2013.01.009 |
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