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c-Jun N-terminal Kinase (JNK)-dependent Acute Liver Injury from Acetaminophen or Tumor Necrosis Factor (TNF) Requires Mitochondrial Sab Protein Expression in Mice

Sustained JNK activation plays a critical role in hepatotoxicity by acetaminophen or GalN/TNF-α. To address the importance of JNK translocation to mitochondria that accompanies sustained activation in these models, we assessed the importance of the expression of a potential initial target of JNK in...

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Detaylı Bibliyografya
Asıl Yazarlar: Win, Sanda, Than, Tin Aung, Han, Derick, Petrovic, Lydia M., Kaplowitz, Neil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186406/
https://ncbi.nlm.nih.gov/pubmed/21844199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.276089
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