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Mechanisms of Pathogenesis in Drug Hepatotoxicity Putting the Stress on Mitochondria
Mitochondria play key roles in aerobic life and in cell death. Thus, interference of normal mitochondrial function impairs cellular energy and lipid metabolism and leads to the unleashing of mediators of cell death. The role of mitochondria in cell death due to drug hepatotoxicity has been receiving...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Pharmacology and Experimental Therapeutics
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895369/ https://ncbi.nlm.nih.gov/pubmed/20368370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.10.2.7 |
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