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Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are prototypic growth factors and receptor tyrosine kinases which have critical functions in development. We show that PDGFs share a conserved region in their prodomain sequences which can remain noncovalently associated with the m...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895058/ https://ncbi.nlm.nih.gov/pubmed/20534510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000806107 |
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