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Structural basis of Semaphorin-Plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1

Repulsive signaling by Semaphorins and Plexins is crucial for the development and homeostasis of the nervous, immune and cardiovascular systems. Sema7A acts as both an immune and a neural Semaphorin through PlexinC1, and A39R is a Sema7A mimic secreted by poxviruses. We report the structures of Sema...

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Detalhes bibliográficos
Main Authors: Liu, Heli, Juo, Z. Sean, Hye-Ryong Shim, Ann, Focia, Pamela J., Chen, Xiaoyan, Garcia, K. Christopher, He, Xiaolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936782/
https://ncbi.nlm.nih.gov/pubmed/20727575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.07.040
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