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Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling
Ligand-directed signaling has been suggested as a basis for the differences in responses evoked by otherwise receptor-selective agonists. The underlying mechanisms are not understood, yet clearer definition of this concept may be helpful in the development of novel, pathway-selective therapeutic age...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895055/ https://ncbi.nlm.nih.gov/pubmed/20534436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000751107 |
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