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Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling

Ligand-directed signaling has been suggested as a basis for the differences in responses evoked by otherwise receptor-selective agonists. The underlying mechanisms are not understood, yet clearer definition of this concept may be helpful in the development of novel, pathway-selective therapeutic age...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Melief, Erica J., Miyatake, Mayumi, Bruchas, Michael R., Chavkin, Charles
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895055/
https://ncbi.nlm.nih.gov/pubmed/20534436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000751107
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