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Kinase Cascades and Ligand-Directed Signaling at the Kappa Opioid Receptor

BACKGROUND AND RATIONALE: The dynorphin / kappa-opioid receptor (KOR) system has been implicated as a critical component of the stress response. Stress-induced activation of dynorphin-KOR is well-known to produce analgesia, and more recently it has been implicated as a mediator of stress-induced res...

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Detalhes bibliográficos
Main Authors: Bruchas, Michael R., Chavkin, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671863/
https://ncbi.nlm.nih.gov/pubmed/20401607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1806-y
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