UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity

BACKGROUND: The uncoupling protein 1 (UCP1) is a hallmark of brown adipocytes and pivotal for cold- and diet-induced thermogenesis. METHODOLOGY/PRINCIPAL FINDINGS: Here we report that cyclooxygenase (COX) activity and prostaglandin E(2) (PGE(2)) are crucially involved in induction of UCP1 expression...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Madsen, Lise, Pedersen, Lone M., Lillefosse, Haldis Haukaas, Fjære, Even, Bronstad, Ingeborg, Hao, Qin, Petersen, Rasmus K., Hallenborg, Philip, Ma, Tao, De Matteis, Rita, Araujo, Pedro, Mercader, Josep, Bonet, M. Luisa, Hansen, Jacob B., Cannon, Barbara, Nedergaard, Jan, Wang, Jun, Cinti, Saverio, Voshol, Peter, Døskeland, Stein Ove, Kristiansen, Karsten
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894971/
https://ncbi.nlm.nih.gov/pubmed/20613988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011391
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