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Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation

Adipocyte precursor cells give raise to two major cell populations with different physiological roles: white and brown adipocytes. Here we demonstrate that the retinoblastoma protein (pRB) regulates white vs. brown adipocyte differentiation. Functional inactivation of pRB in wild-type mouse embryo f...

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Detalhes bibliográficos
Main Authors: Hansen, Jacob B., Jørgensen, Claus, Petersen, Rasmus K., Hallenborg, Philip, De Matteis, Rita, Bøye, Hans A., Petrovic, Natasa, Enerbäck, Sven, Nedergaard, Jan, Cinti, Saverio, Riele, Hein te, Kristiansen, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384703/
https://ncbi.nlm.nih.gov/pubmed/15024128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0301964101
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