Effects of Wnt Signaling on Brown Adipocyte Differentiation and Metabolism Mediated by PGC-1α

Activation of canonical Wnt signaling inhibits brown adipogenesis of cultured cells by impeding induction of PPARγ and C/EBPα. Although enforced expression of these adipogenic transcription factors restores lipid accumulation and expression of FABP4 in Wnt-expressing cells, additional expression of...

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Main Authors: Kang, Sona, Bajnok, Laszlo, Longo, Kenneth A., Petersen, Rasmus K., Hansen, Jacob B., Kristiansen, Karsten, MacDougald, Ormond A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC548004/
https://ncbi.nlm.nih.gov/pubmed/15684380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1272-1282.2005
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