Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

Adrenergic stimulation of brown adipocytes (BA) induces mitochondrial uncoupling, thereby increasing energy expenditure by shifting nutrient oxidation towards thermogenesis. Here we describe that mitochondrial dynamics is a physiological regulator of adrenergically-induced changes in energy expendit...

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Hlavní autoři: Wikstrom, Jakob D, Mahdaviani, Kiana, Liesa, Marc, Sereda, Samuel B, Si, Yaguang, Las, Guy, Twig, Gilad, Petrovic, Natasa, Zingaretti, Cristina, Graham, Adam, Cinti, Saverio, Corkey, Barbara E, Cannon, Barbara, Nedergaard, Jan, Shirihai, Orian S
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983686/
https://ncbi.nlm.nih.gov/pubmed/24431221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201385014
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