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Fatty Acids Suppress Autophagic Turnover in β-Cells
Recent studies have shown that autophagy is essential for proper β-cell function and survival. However, it is yet unclear under what pathogenic conditions autophagy is inhibited in β-cells. Here, we report that long term exposure to fatty acids and glucose block autophagic flux in β-cells, contribut...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234912/ https://ncbi.nlm.nih.gov/pubmed/21859708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.242412 |
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