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Molecular-Targeted Antitumor Agents 19: Furospongolide from a Marine Lendenfeldia sp. Sponge Inhibits Hypoxia-Inducible Factor-1 (HIF-1) Activation in Breast Tumor Cells
[Image: see text] A natural product chemistry-based approach was employed to discover small molecule inhibitors of the important tumor-selective molecular target hypoxia-inducible factor-1 (HIF-1). Bioassay-guided isolation of an active lipid extract of a Saipan collection of the marine sponge Lende...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893247/ https://ncbi.nlm.nih.gov/pubmed/18989978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np800342s |
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