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Molecular-Targeted Antitumor Agents 15: Neolamellarins from the Marine Sponge Dendrilla nigra Inhibit Hypoxia-Inducible Factor-1 (HIF-1) Activation and Secreted Vascular Endothelial Growth Factor (VEGF) Production in Breast Tumor Cells

The transcription factor Hypoxia-Inducible Factor 1 (HIF-1) has emerged as a major antitumor molecular target. Inhibition of HIF-1 activation has been shown to suppress the growth, survival, and metastatic spread of hypoxic tumors. The NCI Open Repository of marine invertebrates and algae lipid extr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Liu, Rui, Liu, Yang, Zhou, Yu-Dong, Nagle, Dale G.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914556/
https://ncbi.nlm.nih.gov/pubmed/17958397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np070206e
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