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Hypoxia-Selective Antitumor Agents: Norsesterterpene Peroxides from the Marine Sponge Diacarnus levii Preferentially Suppress the Growth of Tumor Cells under Hypoxic Conditions

As part of an ongoing research program to discover natural products that suppress the hypoxia-activated tumor survival pathways, the lipid extract of the Papua New Guinea marine sponge Diacarnus levii was found to suppress hypoxia-induced HIF-1 activation and hypoxic tumor cell survival. Bioassay-gu...

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Detaylı Bibliyografya
Asıl Yazarlar: Dai, Jingqiu, Liu, Yang, Zhou, Yu-Dong, Nagle, Dale G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910712/
https://ncbi.nlm.nih.gov/pubmed/17253866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np0604883
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