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Structures and Potential Antitumor Activity of Sesterterpenes from the Marine Sponge Hyrtios communis (Carter, 1885)

The extract of marine sponge Hyrtios communis (Carter, 1885) (Order Dictyoceratida, Family Thorectidae) was found to inhibit activation of the transcription factor hypoxia-inducible factor-1 (HIF-1) in T47D human breast tumor cells. Bioassay-guided isolation led to the identification of six new (1–6...

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Detalhes bibliográficos
Main Authors: Li, Jun, Du, Lin, Kelly, Michelle, Zhou, Yu-Dong, Nagle, Dale G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809078/
https://ncbi.nlm.nih.gov/pubmed/23944963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400350k
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