Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts
Osteoclasts express the αvβ3 integrin, an adhesion receptor that has been implicated in bone resorption and that is therefore a potential therapeutic target. To assess the role of this heterodimer in skeletal development in vivo, we engineered mice in which the gene for the β3 integrin subunit was d...
محفوظ في:
| الحاوية / القاعدة: | J Clin Invest |
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| المؤلفون الرئيسيون: | , , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Clinical Investigation
2000
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10683372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8905 |
| الوسوم: |
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