Загрузка...

Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts

Osteoclasts express the αvβ3 integrin, an adhesion receptor that has been implicated in bone resorption and that is therefore a potential therapeutic target. To assess the role of this heterodimer in skeletal development in vivo, we engineered mice in which the gene for the β3 integrin subunit was d...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: McHugh, Kevin P., Hodivala-Dilke, Kairbaan, Zheng, Ming-Hao, Namba, Noriyuki, Lam, Jonathan, Novack, Deborah, Feng, Xu, Ross, F. Patrick, Hynes, Richard O., Teitelbaum, Steven L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC289172/
https://ncbi.nlm.nih.gov/pubmed/10683372
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!