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Hematopoietic stem cell function requires 12/15-lipoxygenase–dependent fatty acid metabolism
Fatty acid metabolism governs multiple intracellular signaling pathways in many cell types, but its role in hematopoietic stem cells (HSCs) is largely unknown. Herein, we establish a critical role for 12/15-lipoxygenase (12/15-LOX)–mediated unsaturated fatty acid metabolism in HSC function. HSCs fro...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890149/ https://ncbi.nlm.nih.gov/pubmed/20357242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-243139 |
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