12/15-Lipoxygenase-Dependent Myeloid Production of Interleukin-12 Is Essential for Resistance to Chronic Toxoplasmosis

Interleukin-12 (IL-12) is critical for resistance to Toxoplasma gondii during both the acute and chronic stages of infection. However, the cellular and molecular pathways that regulate IL-12 production during chronic toxoplasmosis are incompletely defined. We recently discovered that 12/15-lipoxygen...

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Autori principali: Middleton, Melissa K., Zukas, Alicia M., Rubinstein, Tanya, Kinder, Michelle, Wilson, Emma H., Zhu, Peijuan, Blair, Ian A., Hunter, Christopher A., Puré, Ellen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786478/
https://ncbi.nlm.nih.gov/pubmed/19822654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00560-09
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